Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.

Kim TE, Tsuboyama K, Houliston S, Martell CM, Phoumyvong CM, Lemak A, Haddox HK, Arrowsmith CH, Rocklin GJ.Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2122676119. doi: 10.1073/pnas.2122676119. Epub 2022 Oct 3.