1977-  Graduated from Medical School, The University of Tokyo (UTokyo)
1977-  Internship in Internal Medicine, UTokyo Hospital
1979-  Clinical Fellow in Internal Medicine, UTokyo(Komagome Hospital)
1985-  Research Fellow, Dept. of Biology, MIT
1989-  Assistant Professor, Third Department of Internal Medicine, UTokyo
1996-  Professor, Dept. of Molecular Biology and Medicine, RCAST, UTokyo
2002-  Professor, Dept. of Systems Biology and Medicine, RCAST, UTokyo
2004-  Professor, RCAST, UTokyo (~2018.03)
2018-  Emeritus Professor, UTokyo


After human genome sequencing, now we are able to identify target proteins for drug development aiming cancer and metabolic disorders. We are focusing membrane proteins and nuclear proteins regulating human health and disease. We express these target proteins and make crystals to determine super fine structure. Using this information with the help of high performance computing, we are developing tools for dynamical analysis of protein-protein interaction or proteinlow molecular weight compounds interaction.