YEAR
- 2018.10.02 Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability-High Colorectal Cancers Sato K, Kawazu M, Yamamoto Y, Ueno T, Kojima S, Nagae G, Abe H, Soda M, Oga T, Kohsaka S, Sai E, Yamashita Y, Iinuma H, Fukayama M, Aburatani H, Watanabe T, Mano H.Clin Cancer Res. 2019 01 01;25(1):378-389. doi: 10.1158/1078-0432.CCR-18-1574
- 2018.08.30 Engineered CRISPR-Cas9 nuclease with expanded targeting space Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O.Science. 2018 09 21;361(6408):1259-1262. doi: 10.1126/science.aas9129
- 2018.08.29 Structural mechanisms of selectivity and gating in anion channelrhodopsins. Kato HE, Kim YS, Paggi JM, Evans KE, Allen WE, Richardson C, Inoue K, Ito S, Ramakrishnan C, Fenno LE, Yamashita K, Hilger D, Lee SY, Berndt A, Shen K, Kandori H, Dror RO, Kobilka BK, Deisseroth K.Nature. 2018 09;561(7723):349-354. doi: 10.1038/s41586-018-0504-5
- 2018.08.29 Crystal structure of the natural anion-conducting channelrhodopsin GtACR1. Kim YS, Kato HE, Yamashita K, Ito S, Inoue K, Ramakrishnan C, Fenno LE, Evans KE, Paggi JM, Dror RO, Kandori H, Kobilka BK, Deisseroth K.Nature. 2018 09;561(7723):343-348. doi: 10.1038/s41586-018-0511-6
- 2018.08.18 Multiplicity in Long Noncoding RNA Biomedical Sciences R. Kurokawa, R. Komiya, T. Oyoshi, Y. Matsuno, H. Tani, M. Katahira, K. Hitachi, Y. Iwashita, T. Yamashita, K. Kondo, R. Yoneda, Y. Yamaoki, N. Ueda, T. Mashima, N. Kobayashi, T. Nagata, A. Kiyoishi, M. Miyake, F. Kano, M. Murata1, N. Hamad, K. Sasaki, N. ShojiBiomedical Sciences. 4, 18-23 (2018)
- 2018.08.01 Novel chemical compound SINCRO with dual function in STING-type I interferon and tumor cell death pathways. Kimura Y, Negishi H, Matsuda A, Endo N, Hangai S, Inoue A, Nishio J, Taniguchi T, Yanai H.Cancer Sci. 2018 Sep;109(9):2687-2696. doi: 10.1111/cas.13726
- 2018.07.05 Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody. Miyanabe K, Yamashita T, Abe Y, Akiba H, Takamatsu Y, Nakakido M, Hamakubo T, Ueda T, Caaveiro JMM, Tsumoto K.Biochemistry. 2018 07 17;57(28):4177-4185. doi: 10.1021/acs.biochem.8b00592
- 2018.06.22 What consequence is anticipated by the emergence of novel SPPARMa agent developed so as to achieve an improved safety/efficacy balance? Motonobu Anai, Toshiya Tanaka, Tatsuhiko Kodama.Jpn Pharmacol Ther. 46: 471-480 (2018).
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