Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface

T. Yamashita, E. Mizohata, S. Nagatoishi, T. Watanabe, M. Nakakido, H. Iwanari, Y. Mochizuki, T. Nakayama, Y. Kado, Y. Yokota, H. Matsumura, T. Kawamura, T. Kodama, T. Hamakubo, T. Inoue, H. Fujitani, and K. Tsumoto Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface Structure 27, 519–527 (2019) ; doi: 10.1016/j.str.2018.11.002 (プレスリリース: https://www.rcast.u-tokyo.ac.jp/ja/news/release/190107.html)

Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X- chromosome inactivation

Y. Matsuno, T. Yamashita, M. Wagatsuma, and H. Yamakage
Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X- chromosome inactivation Mobile DNA 10, Article number: 33 (2019)
https://doi.org/10.1186/s13100-019-0173-4

抗体医薬品設計に IT 革命を: 理論と計算による挑戦

山下雄史 抗体医薬品設計に IT 革命を: 理論と計算による挑戦 月刊「細胞」(The Cell) 51(7), 344-347 (2019).

A SNP in a Steroidogenic Enzyme Is Associated with Phenotypic Sex in Seriola Fishes

T. Koyama, M. Nakamoto#, K. Morishima#, R. Yamashita#, T. Yamashita#, K. Sasaki, Y. Kuruma, N. Mizuno, M. Suzuki, Y. Okada, R. Ieda, T. Uchino, S. Tasumi, S. Hosoya, S. Uno, J. Koyama, A. Toyoda, K. Kikuchi*, and T. Sakamoto* (* Corresponding author; #Equally contributed) A SNP in a Steroidogenic Enzyme Is Associated with Phenotypic Sex in Seriola Fishes Current Biology 29, pp. 1901-1909 (2019). https://doi.org/10.1016/j.cub.2019.04.069

Fast and global detection of periodic sequence repeats in large genomic resources

Mori H, Evans-Yamamoto D, Ishiguro S, Tomita M & Yachie N   Fast and global detection of periodic sequence repeats in large genomic resources Nucleic Acids Research gky890, https://doi.org/10.1093/nar/gky890