YEAR
- 2018.08.01 Novel chemical compound SINCRO with dual function in STING-type I interferon and tumor cell death pathways. Kimura Y, Negishi H, Matsuda A, Endo N, Hangai S, Inoue A, Nishio J, Taniguchi T, Yanai H.Cancer Sci. 2018 Sep;109(9):2687-2696. doi: 10.1111/cas.13726
- 2018.07.05 Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody. Miyanabe K, Yamashita T, Abe Y, Akiba H, Takamatsu Y, Nakakido M, Hamakubo T, Ueda T, Caaveiro JMM, Tsumoto K.Biochemistry. 2018 07 17;57(28):4177-4185. doi: 10.1021/acs.biochem.8b00592
- 2018.06.22 What consequence is anticipated by the emergence of novel SPPARMa agent developed so as to achieve an improved safety/efficacy balance? Motonobu Anai, Toshiya Tanaka, Tatsuhiko Kodama.Jpn Pharmacol Ther. 46: 471-480 (2018).
- 2018.06.15 Ghost cytometry. Ota S, Horisaki R, Kawamura Y, Ugawa M, Sato I, Hashimoto K, Kamesawa R, Setoyama K, Yamaguchi S, Fujiu K, Waki K, Noji H.Science. 2018 06 15;360(6394):1246-1251. doi: 10.1126/science.aan0096
- 2018.05.15 Discovery of peroxisome proliferator-activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line. Tachibana K, Yuzuriha T, Tabata R, Fukuda S, Maegawa T, Takahashi R, Tanimoto K, Tsujino H, Nunomura K, Lin B, Matsuura Y, Tanaka T, Hamakubo T, Sakai J, Kodama T, Kobayashi T, Ishimoto K, Miyachi H, Doi T.J. Biol. Chem. 2018 06 29;293(26):10333-10343. doi: 10.1074/jbc.RA118.002077
- 2018.05.03 Structural Properties of the Human Protease-Activated Receptor 1 Changing by a Strong Antagonist. Spoerri PM, Kato HE, Pfreundschuh M, Mari SA, Serdiuk T, Thoma J, Sapra KT, Zhang C, Kobilka BK, Müller DJ.Structure. 2018 06 05;26(6):829-838.e4. doi: 10.1016/j.str.2018.03.020
- 2018.04.30 Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice. Yanai H, Chiba S, Hangai S, Kometani K, Inoue A, Kimura Y, Abe T, Kiyonari H, Nishio J, Taguchi-Atarashi N, Mizushima Y, Negishi H, Grosschedl R, Taniguchi T.Proc. Natl. Acad. Sci. U.S.A. 2018 05 15;115(20):5253-5258. doi: 10.1073/pnas.1803936115
- 2018.04.30 Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry. Obi N, Fukuda T, Nakayama N, Ervin J, Bando Y, Nishimura T, Nagatoishi S, Tsumoto K, Kawamura T.Rapid Commun. Mass Spectrom. 2018 Apr 30;32(8):665-671. doi: 10.1002/rcm.8083
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