The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice.

Yu B, Ueta H, Kitazawa Y, Tanaka T, Adachi K, Kimura H, Morita M, Sawanobori Y, Qian HX, Kodama T, Matsuno K. The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice. Hepatology. 2012 Oct;56(4):1532-45. doi: 10.1002/hep.25795.

Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities.

Yu B, Ueta H, Kitazawa Y, Tanaka T, Adachi K, Kimura H, Morita M, Sawanobori Y, Qian HX, Kodama T, Matsuno K. Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities. Hepatology. 2012 Oct;56(4):1532-45. doi: 10.1002/hep.25795.

In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding.

Fujita K, Iwasaki M, Ochi H, Fukuda T, Ma C, Miyamoto T, Takitani K, Negishi-Koga T, Sunamura S, Kodama T, Takayanagi H, Tamai H, Kato S, Arai H, Shinomiya K, Itoh H, Okawa A, Takeda S. In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding. Nat Med. 2012 Mar 4;18(4):589-94. doi: 10.1038/nm.2659. Erratum in: Nat Med. 2012 Sep;18(9):1445.

Determination of physiological plasma pentraxin 3 (PTX3) levels in healthy populations.

Inoue K, Kodama T, Daida H. Determination of physiological plasma pentraxin 3 (PTX3) levels in healthy populations. Int J Vasc Med. 2012;2012:657025. doi: 10.1155/2012/657025. Epub 2012 Jan 4.

Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface.

Daigo K, Yamaguchi N, Kawamura T, Matsubara K, Jiang S, Ohashi R, Sudou Y, Kodama T, Naito M, Inoue K, Hamakubo T. Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface. Mol Cell Proteomics. 2012 Jun;11(6):M111.015073. doi: 10.1074/mcp.M111.015073. Epub 2012 Jan 25.

A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization.

Kawamura T, Ogawa Y, Nakamura Y, Nakamizo S, Ohta Y, Nakano H, Kabashima K, Katayama I, Koizumi S, Kodama T, Nakao A, Shimada S. A single amino acid of toll-like receptor 4 that is pivotal for its signal transduction and subcellular localization. J Clin Invest. 2012 Feb;122(2):722-32. doi: 10.1172/JCI58618. Epub 2012 Jan 3.

Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study).

Ohta Y, Kodama T, Ihara S. Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Oct;84(4 Pt 1):041922. Epub 2011 Oct 19.

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M. Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20725-9. doi: 10.1073/pnas.1108462109. Epub 2011 Dec 5.

Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.

Osawa T, Muramatsu M, Wang F, Tsuchida R, Kodama T, Minami T, Shibuya M. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20725-9. doi: 10.1073/pnas.1108462109. Epub 2011 Dec 5.

Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer.

Fujimura T, Takahashi S, Urano T, Tanaka T, Zhang W, Azuma K, Takayama K, Obinata D, Murata T, Horie-Inoue K, Kodama T, Ouchi Y, Homma Y, Inoue S. Clinical significance of steroid and xenobiotic receptor and its targeted gene CYP3A4 in human prostate cancer. Cancer Sci. 2012 Feb;103(2):176-80. doi: 10.1111/j.1349-7006.2011.02143.x. Epub 2011 Nov 27.

Heterogeneity in immunohistochemical, genomic, and biological properties of human lymphatic endothelial cells between initial and collecting lymph vessels.

Fujimura T, Takahashi S, Urano T, Tanaka T, Zhang W, Azuma K, Takayama K, Obinata D, Murata T, Horie-Inoue K, Kodama T, Ouchi Y, Homma Y, Inoue S. Heterogeneity in immunohistochemical, genomic, and biological properties of human lymphatic endothelial cells between initial and collecting lymph vessels. Cancer Sci. 2012 Feb;103(2):176-80. doi: 10.1111/j.1349-7006.2011.02143.x. Epub 2011 Nov 27.

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

Waki H, Nakamura M, Yamauchi T, Wakabayashi K, Yu J, Hirose-Yotsuya L, Take K, Sun W, Iwabu M, Okada-Iwabu M, Fujita T, Aoyama T, Tsutsumi S, Ueki K, Kodama T, Sakai J, Aburatani H, Kadowaki T. Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. PLoS Genet. 2011 Oct;7(10):e1002311. doi: 10.1371/journal.pgen.1002311. Epub 2011 Oct 20.

Characterization and microarray analysis of genes in human lymphatic endothelial cells from patients with breast cancer.

Negishi-Koga T, Shinohara M, Komatsu N, Bito H, Kodama T, Friedel RH, Takayanagi H. Characterization and microarray analysis of genes in human lymphatic endothelial cells from patients with breast cancer. Nat Med. 2011 Oct 23;17(11):1473-80. doi: 10.1038/nm.2489.

Alzheimer’s disease: cholesterol, membrane rafts, isoprenoids and statins.

Nakashima T, Hayashi M, Fukunaga T, Kurata K, Oh-Hora M, Feng JQ, Bonewald LF, Kodama T, Wutz A, Wagner EF, Penninger JM, Takayanagi H. Alzheimer’s disease: cholesterol, membrane rafts, isoprenoids and statins. Nat Med. 2011 Sep 11;17(10):1231-4. doi: 10.1038/nm.2452.

Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis.

Wang F, Osawa T, Tsuchida R, Yuasa Y, Shibuya M. Downregulation of receptor for activated C-kinase 1 (RACK1) suppresses tumor growth by inhibiting tumor cell proliferation and tumor-associated angiogenesis. Cancer Sci. 2011 Nov;102(11):2007-13. doi: 10.1111/j.1349-7006.2011.02065.x. Epub 2011 Sep 22.

Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells.

Osawa T, Davies D, Hartley JA. Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells. Cell Death Dis. 2011 Aug 4;2:e187. doi: 10.1038/cddis.2011.70.