Blimp1-mediated repression of negative regulators is required for osteoclast differentiation.

Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro J, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, Shibuya M. Blimp1-mediated repression of negative regulators is required for osteoclast differentiation. Cancer Res. 2013 May 15;73(10):3019-28. doi: 10.1158/0008-5472.CAN-12-3231. Epub 2013 Mar 14.

Reciprocal contribution of pentraxin 3 and C-reactive protein to obesity and metabolic syndrome.

Yumura K, Ui M, Doi H, Hamakubo T, Kodama T, Tsumoto K, Sugiyama A. Reciprocal contribution of pentraxin 3 and C-reactive protein to obesity and metabolic syndrome. Protein Sci. 2013 Feb;22(2):213-21. doi: 10.1002/pro.2203. Epub 2013 Jan 4.

RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand.

Mochizuki Y, Ohashi R, Kawamura T, Iwanari H, Kodama T, Naito M, Hamakubo T. RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand. J Biol Chem. 2013 Jan 11;288(2):1009-21. doi: 10.1074/jbc.M112.395087. Epub 2012 Nov 27.

Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-kappaB (RANK).

Papantonis A, Kohro T, Baboo S, Larkin JD, Deng B, Short P, Tsutsumi S, Taylor S, Kanki Y, Kobayashi M, Li G, Poh HM, Ruan X, Aburatani H, Ruan Y, Kodama T, Wada Y, Cook PR. Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-kappaB (RANK). EMBO J. 2012 Nov 28;31(23):4404-14. doi: 10.1038/emboj.2012.288. Epub 2012 Oct 26.

Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3.

Kusano-Arai O, Iwanari H, Mochizuki Y, Nakata H, Kodama T, Kitoh T, Hamakubo T. Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3. Hybridoma (Larchmt). 2012 Oct;31(5):325-32. doi: 10.1089/hyb.2012.0014.

Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines.

Suzuki T, Tsuzuku J, Hayashi A, Shiomi Y, Iwanari H, Mochizuki Y, Hamakubo T, Kodama T, Nishitani H, Masai H, Yamamoto T. Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. J Biol Chem. 2012 Nov 23;287(48):40256-65. doi: 10.1074/jbc.M112.353805. Epub 2012 Oct 12.

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

Ohta Y, Nishiyama A, Wada Y, Ruan Y, Kodama T, Tsuboi T, Tokihiro T, Ihara S. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Aug;86(2 Pt 1):021918. Epub 2012 Aug 21.

The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.

Matsuura Y, Hatakeyama K, Imamura T, Tsuruda T, Shibata Y, Kodama T, Kitamura K, Asada Y. The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Atheroscler Thromb. 2012;19(9):837-45. Epub 2012 Jul 11.

COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.

Pandya K, Kohro T, Mimura I, Kobayashi M, Wada Y, Kodama T, Smithies O. COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells. Gene Expr. 2012;15(4):183-98.

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.

Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshikawa M, Yoshida GJ, Wada T, Masuko T, Mogushi K, Tanaka H, Osawa T, Kanki Y, Minami T, Aburatani H, Ohmura M, Kubo A, Suematsu M, Takahashi K, Saya H, Nagano O. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun. 2012 Jun 6;3:883. doi: 10.1038/ncomms1892.

Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages.

Kudo S, Caaveiro JM, Miyafusa T, Goda S, Ishii K, Matsuura T, Sudou Y, Kodama T, Hamakubo T, Tsumoto K. Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages. Mol Biosyst. 2012 Aug;8(8):2050-3. doi: 10.1039/c2mb25161b. Epub 2012 Jun 7.

Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.

Mimura I, Nangaku M, Kanki Y, Tsutsumi S, Inoue T, Kohro T, Yamamoto S, Fujita T, Shimamura T, Suehiro J, Taguchi A, Kobayashi M, Tanimura K, Inagaki T, Tanaka T, Hamakubo T, Sakai J, Aburatani H, Kodama T, Wada Y. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol Cell Biol. 2012 Aug;32(15):3018-32. doi: 10.1128/MCB.06643-11. Epub 2012 May 29.

Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.

Mimura I, Nangaku M, Kanki Y, Tsutsumi S, Inoue T, Kohro T, Yamamoto S, Fujita T, Shimamura T, Suehiro J, Taguchi A, Kobayashi M, Tanimura K, Inagaki T, Tanaka T, Hamakubo T, Sakai J, Aburatani H, Kodama T, Wada Y. Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells. Mol Cell Biol. 2012 Aug;32(15):3018-32. doi: 10.1128/MCB.06643-11. Epub 2012 May 29.

Influence of statins on glucose tolerance in patients with type 2 diabetes mellitus: subanalysis of the collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study).

Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H. Influence of statins on glucose tolerance in patients with type 2 diabetes mellitus: subanalysis of the collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Nature. 2012 May 3;485(7396):69-74. doi: 10.1038/nature11000.

Novel repressor regulates insulin sensitivity through interaction with Foxo1.

Nakae J, Cao Y, Hakuno F, Takemori H, Kawano Y, Sekioka R, Abe T, Kiyonari H, Tanaka T, Sakai J, Takahashi S, Itoh H. Novel repressor regulates insulin sensitivity through interaction with Foxo1. EMBO J. 2012 May 16;31(10):2275-95. doi: 10.1038/emboj.2012.97. Epub 2012 Apr 17.

The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice.

Yu B, Ueta H, Kitazawa Y, Tanaka T, Adachi K, Kimura H, Morita M, Sawanobori Y, Qian HX, Kodama T, Matsuno K. The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice. Hepatology. 2012 Oct;56(4):1532-45. doi: 10.1002/hep.25795.