Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.

Nishimura T, Kawamura T, Sugihara Y, Bando Y, Sakamoto S, Nomura M, Ikeda N, Ohira T, Fujimoto J, Tojo H, Hamakubo T, Kodama T, Andersson R, Fehniger TE, Kato H, Marko-Varga G. Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies. Clin Transl Med. 2014 Nov 22;3(1):61. doi: 10.1186/s40169-014-0038-x. eCollection 2014 Dec.

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

Kawato T, Mizohata E, Shimizu Y, Meshizuka T, Yamamoto T, Takasu N, Matsuoka M, Matsumura H, Kodama T, Kanai M, Doi H, Inoue T, Sugiyama A. Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Biosci Biotechnol Biochem. 2015;79(4):640-2. doi: 10.1080/09168451.2014.991692. Epub 2015 Jan 3.

Revolution of nephrology research by deep sequencing: ChIP-seq and RNA-seq.

Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, Yamasaki A, Tsurutani Y, Yoshida A, Chikaoka Y, Nakamura K, Magoori K, Nakaki R, Osborne TF, Fukami K, Aburatani H, Kodama T, Sakai J. Revolution of nephrology research by deep sequencing: ChIP-seq and RNA-seq. J Biol Chem. 2015 Feb 13;290(7):4163-77. doi: 10.1074/jbc.M114.626929. Epub 2014 Dec 22.

The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis.

Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, Yamasaki A, Tsurutani Y, Yoshida A, Chikaoka Y, Nakamura K, Magoori K, Nakaki R, Osborne TF, Fukami K, Aburatani H, Kodama T, Sakai J. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015 Feb 13;290(7):4163-77. doi: 10.1074/jbc.M114.626929. Epub 2014 Dec 22.

Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells.

Razvina O, Jiang S, Matsubara K, Ohashi R, Hasegawa G, Aoyama T, Daigo K, Kodama T, Hamakubo T, Naito M. Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells. Exp Mol Pathol. 2015 Feb;98(1):33-40. doi: 10.1016/j.yexmp.2014.11.009. Epub 2014 Nov 20.

Different distribution of pentraxin 3 and C-reactive protein in coronary atherosclerotic plaques.

Kawato T, Mizohata E, Meshizuka T, Doi H, Kawamura T, Matsumura H, Yumura K, Tsumoto K, Kodama T, Inoue T, Sugiyama A. Different distribution of pentraxin 3 and C-reactive protein in coronary atherosclerotic plaques. J Biosci Bioeng. 2015 Jun;119(6):642-7. doi: 10.1016/j.jbiosc.2014.10.025. Epub 2014 Nov 26.

Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression.

Suehiro J, Kanki Y, Makihara C, Schadler K, Miura M, Manabe Y, Aburatani H, Kodama T, Minami T. Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression. J Biol Chem. 2014 Oct 17;289(42):29044-59. doi: 10.1074/jbc.M114.555235. Epub 2014 Aug 25.

PPARβ/δ activation of CD300a controls intestinal immunity.

Tanaka T, Tahara-Hanaoka S, Nabekura T, Ikeda K, Jiang S, Tsutsumi S, Inagaki T, Magoori K, Higurashi T, Takahashi H, Tachibana K, Tsurutani Y, Raza S, Anai M, Minami T, Wada Y, Yokote K, Doi T, Hamakubo T, Auwerx J, Gonzalez FJ, Nakajima A, Aburatani H, Naito M, Shibuya A, Kodama T, Sakai J. PPARβ/δ activation of CD300a controls intestinal immunity. Sci Rep. 2014 Jun 24;4:5412. doi: 10.1038/srep05412.

Osteoprotection by semaphorin 3A.

Fujiwara K, Koyama K, Suga K, Ikemura M, Saito Y, Hino A, Iwanari H, Kusano-Arai O, Mitsui K, Kasahara H, Fukayama M, Kodama T, Hamakubo T, Momose T. Osteoprotection by semaphorin 3A. EJNMMI Res. 2014 Jun 1;4:29. doi: 10.1186/s13550-014-0029-3. eCollection 2014.

Vitamin E decreases bone mass by stimulating osteoclast fusion.

Yamashita T, Ueda A, Mitsui T, Tomonaga A, Matsumoto S, Kodama T, Fujitani H. Vitamin E decreases bone mass by stimulating osteoclast fusion. Chem Pharm Bull (Tokyo). 2014;62(7):661-7.

Pentraxin 3: a novel biomarker for inflammatory cardiovascular disease.

Tanaka T, Tahara-Hanaoka S, Nabekura T, Ikeda K, Jiang S, Tsutsumi S, Inagaki T, Magoori K, Higurashi T, Takahashi H, Tachibana K, Tsurutani Y, Raza S, Anai M, Minami T, Wada Y, Yokote K, Doi T, Hamakubo T, Auwerx J, Gonzalez FJ, Nakajima A, et al. Pentraxin 3: a novel biomarker for inflammatory cardiovascular disease. Sci Rep. 2014 Jun 24;4:5412. doi: 10.1038/srep05412.

Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells.

Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, Kimura H, Kobayashi M, Taguchi A, Tsutsumi S, Iwanari H, Yamamoto S, Aruga H, Dong S, Stevens JF, Poh HM, Yamamoto K, Kawamura T, Mimura I, Suehiro J, Sugiyama A, Kaneki K, et al. Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells. PLoS One. 2014 May 5;9(5):e96005. doi: 10.1371/journal.pone.0096005. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99749.

Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency.

Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, Kimura H, Kobayashi M, Taguchi A, Tsutsumi S, Iwanari H, Yamamoto S, Aruga H, Dong S, Stevens JF, Poh HM, Yamamoto K, Kawamura T, Mimura I, Suehiro J, Sugiyama A, Kaneki K, et al. Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. PLoS One. 2014 May 5;9(5):e96005. doi: 10.1371/journal.pone.0096005. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99749.

Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements.

Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro J, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, et al. Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements. Genome Biol. 2014 Apr 10;15(4):R63. doi: 10.1186/gb-2014-15-4-r63.

Cellular-automaton model of the cooperative dynamics of RNA polymerase II during transcription in human cells.

Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro J, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, et al. Cellular-automaton model of the cooperative dynamics of RNA polymerase II during transcription in human cells. Genome Biol. 2014 Apr 10;15(4):R63. doi: 10.1186/gb-2014-15-4-r63.

Suppression of bone formation by osteoclastic expression of semaphorin 4D.

Kudo S, Caaveiro JM, Goda S, Nagatoishi S, Ishii K, Matsuura T, Sudou Y, Kodama T, Hamakubo T, Tsumoto K. Suppression of bone formation by osteoclastic expression of semaphorin 4D. Biochemistry. 2014 Mar 25;53(11):1742-52. doi: 10.1021/bi401341g. Epub 2014 Mar 10.