Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury.

Kohno T, Urao N, Ashino T, Sudhahar V, McKinney RD, Hamakubo T, Iwanari H, Ushio-Fukai M, Fukai T. Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):805-13. doi: 10.1161/ATVBAHA.112.300862. Epub 2013 Jan 24.

Host-protective effect of circulating pentraxin 3 (PTX3) and complex formation with neutrophil extracellular traps.

Daigo K, Hamakubo T. Host-protective effect of circulating pentraxin 3 (PTX3) and complex formation with neutrophil extracellular traps. Front Immunol. 2012 Dec 13;3:378. doi: 10.3389/fimmu.2012.00378. eCollection 2012.

Mutations for decreasing the immunogenicity and maintaining the function of core streptavidin.

Yumura K, Ui M, Doi H, Hamakubo T, Kodama T, Tsumoto K, Sugiyama A. Mutations for decreasing the immunogenicity and maintaining the function of core streptavidin. Protein Sci. 2013 Feb;22(2):213-21. doi: 10.1002/pro.2203. Epub 2013 Jan 4.

Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways.

Mochizuki Y, Ohashi R, Kawamura T, Iwanari H, Kodama T, Naito M, Hamakubo T. Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways. J Biol Chem. 2013 Jan 11;288(2):1009-21. doi: 10.1074/jbc.M112.395087. Epub 2012 Nov 27.

Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.

Kusano-Arai O, Iwanari H, Mochizuki Y, Nakata H, Kodama T, Kitoh T, Hamakubo T. Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies. Hybridoma (Larchmt). 2012 Oct;31(5):325-32. doi: 10.1089/hyb.2012.0014.

Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.

Suzuki T, Tsuzuku J, Hayashi A, Shiomi Y, Iwanari H, Mochizuki Y, Hamakubo T, Kodama T, Nishitani H, Masai H, Yamamoto T. Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob. J Biol Chem. 2012 Nov 23;287(48):40256-65. doi: 10.1074/jbc.M112.353805. Epub 2012 Oct 12.

Functional reconstitution of olfactory receptor complex on baculovirus.

Mitsui K, Sakihama T, Takahashi K, Masuda K, Fukuda R, Hamana H, Sato T, Hamakubo T. Functional reconstitution of olfactory receptor complex on baculovirus. Chem Senses. 2012 Nov;37(9):837-47. doi: 10.1093/chemse/bjs067. Epub 2012 Sep 5.

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin.

Kudo S, Caaveiro JM, Miyafusa T, Goda S, Ishii K, Matsuura T, Sudou Y, Kodama T, Hamakubo T, Tsumoto K. Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin. Mol Biosyst. 2012 Aug;8(8):2050-3. doi: 10.1039/c2mb25161b. Epub 2012 Jun 7.

Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1.

Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M. Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1. Biosci Biotechnol Biochem. 2012;76(3):486-94.

Creation and biochemical analysis of a broad-specific claudin binder.

Takahashi A, Saito Y, Kondoh M, Matsushita K, Krug SM, Suzuki H, Tsujino H, Li X, Aoyama H, Matsuhisa K, Uno T, Fromm M, Hamakubo T, Yagi K. Creation and biochemical analysis of a broad-specific claudin binder. Biomaterials. 2012 Apr;33(12):3464-74. doi: 10.1016/j.biomaterials.2012.01.017. Epub 2012 Feb 7.

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody.

Hino T, Arakawa T, Iwanari H, Yurugi-Kobayashi T, Ikeda-Suno C, Nakada-Nakura Y, Kusano-Arai O, Weyand S, Shimamura T, Nomura N, Cameron AD, Kobayashi T, Hamakubo T, Iwata S, Murata T. G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature. 2012 Jan 29;482(7384):237-40. doi: 10.1038/nature10750.

The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular traps.

Daigo K, Yamaguchi N, Kawamura T, Matsubara K, Jiang S, Ohashi R, Sudou Y, Kodama T, Naito M, Inoue K, Hamakubo T. The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular traps. Mol Cell Proteomics. 2012 Jun;11(6):M111.015073. doi: 10.1074/mcp.M111.015073. Epub 2012 Jan 25.

Oxidation of DJ-1 induced by 6-hydroxydopamine decreasing intracellular glutathione.

Miyama A, Saito Y, Yamanaka K, Hayashi K, Hamakubo T, Noguchi N. Oxidation of DJ-1 induced by 6-hydroxydopamine decreasing intracellular glutathione. PLoS One. 2011;6(11):e27883. doi: 10.1371/journal.pone.0027883. Epub 2011 Nov 21.

Basophil-derived mouse mast cell protease 11 induces microvascular leakage and tissue edema in a mast cell-independent manner.

Yamagishi H, Mochizuki Y, Hamakubo T, Obata K, Ugajin T, Sato S, Kawano Y, Minegishi Y, Karasuyama H. Basophil-derived mouse mast cell protease 11 induces microvascular leakage and tissue edema in a mast cell-independent manner. Biochem Biophys Res Commun. 2011 Dec 2;415(4):709-13. doi: 10.1016/j.bbrc.2011.10.150. Epub 2011 Nov 6.

The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice.

Suzuki H, Kondoh M, Kakutani H, Yamane S, Uchida H, Hamakubo T, Yagi K. The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice. Biomaterials. 2012 Jan;33(1):317-24. doi: 10.1016/j.biomaterials.2011.09.048. Epub 2011 Oct 7.

Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.

Daigo K, Kawamura T, Ohta Y, Ohashi R, Katayose S, Tanaka T, Aburatani H, Naito M, Kodama T, Ihara S, Hamakubo T. Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors. J Biol Chem. 2011 Jan 7;286(1):674-86. doi: 10.1074/jbc.M110.154732. Epub 2010 Nov 3. Erratum in: J Biol Chem. 2013 Aug 16;288(33):24161.