Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface

T. Yamashita, E. Mizohata, S. Nagatoishi, T. Watanabe, M. Nakakido, H. Iwanari, Y. Mochizuki, T. Nakayama, Y. Kado, Y. Yokota, H. Matsumura, T. Kawamura, T. Kodama, T. Hamakubo, T. Inoue, H. Fujitani, and K. Tsumoto Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface Structure 27, 519–527 (2019) ; doi: 10.1016/j.str.2018.11.002 (プレスリリース: https://www.rcast.u-tokyo.ac.jp/ja/news/release/190107.html)