The feasibility of an efficient drug design method with high-performance computers.

Yamashita T, Ueda A, Mitsui T, Tomonaga A, Matsumoto S, Kodama T, Fujitani H. The feasibility of an efficient drug design method with high-performance computers. Chem Pharm Bull (Tokyo). 2015;63(3):147-55. doi: 10.1248/cpb.c14-00596.

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

Yamamoto T, Aoki K, Sugiyama A, Doi H, Kodama T, Shimizu Y, Kanai M. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Chem Asian J. 2015 Apr;10(4):1071-8. doi: 10.1002/asia.201500120. Epub 2015 Mar 5.

A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells.

Nishii Y, Yamaguchi M, Kimura Y, Hasegawa T, Aburatani H, Uchida H, Hirata K, Sakuma Y. A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells. Int J Oncol. 2015 Apr;46(4):1781-7. doi: 10.3892/ijo.2015.2880. Epub 2015 Feb 5.

The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss.

Kawato T, Mizohata E, Shimizu Y, Meshizuka T, Yamamoto T, Takasu N, Matsuoka M, Matsumura H, Kodama T, Kanai M, Doi H, Inoue T, Sugiyama A. The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss. J Biochem. 2015 Jun;157(6):467-75. doi: 10.1093/jb/mvv004. Epub 2015 Feb 2.

Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.

Nishimura T, Kawamura T, Sugihara Y, Bando Y, Sakamoto S, Nomura M, Ikeda N, Ohira T, Fujimoto J, Tojo H, Hamakubo T, Kodama T, Andersson R, Fehniger TE, Kato H, Marko-Varga G. Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies. Clin Transl Med. 2014 Nov 22;3(1):61. doi: 10.1186/s40169-014-0038-x. eCollection 2014 Dec.

Clinical initiatives linking Japanese and Swedish healthcare resources on cancer studies utilizing Biobank Repositories.

Nishimura T, Kawamura T, Sugihara Y, Bando Y, Sakamoto S, Nomura M, Ikeda N, Ohira T, Fujimoto J, Tojo H, Hamakubo T, Kodama T, Andersson R, Fehniger TE, Kato H, Marko-Varga G. Clinical initiatives linking Japanese and Swedish healthcare resources on cancer studies utilizing Biobank Repositories. Clin Transl Med. 2014 Nov 22;3(1):61. doi: 10.1186/s40169-014-0038-x. eCollection 2014 Dec.

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

Kawato T, Mizohata E, Shimizu Y, Meshizuka T, Yamamoto T, Takasu N, Matsuoka M, Matsumura H, Kodama T, Kanai M, Doi H, Inoue T, Sugiyama A. Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Biosci Biotechnol Biochem. 2015;79(4):640-2. doi: 10.1080/09168451.2014.991692. Epub 2015 Jan 3.