Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation.

Kikuchi Y, Tsuji E, Yagi K, Matsusaka K, Tsuji S, Kurebayashi J, Ogawa T, Aburatani H, Kaneda A. Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation. Front Genet. 2013 Dec 5;4:271. doi: 10.3389/fgene.2013.00271. eCollection 2013.

Associations of plasma pentraxin 3 and monocyte chemoattractant protein-1 concentrations with cardiovascular disease in patients with chronic kidney disease.

Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh-hora M, Kodama T, Tanaka S, Bluestone JA, Takayanagi H. Associations of plasma pentraxin 3 and monocyte chemoattractant protein-1 concentrations with cardiovascular disease in patients with chronic kidney disease. Nat Med. 2014 Jan;20(1):62-8. doi: 10.1038/nm.3432. Epub 2013 Dec 22.

A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants.

Aramaki S, Hayashi K, Kurimoto K, Ohta H, Yabuta Y, Iwanari H, Mochizuki Y, Hamakubo T, Kato Y, Shirahige K, Saitou M. A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants. Dev Cell. 2013 Dec 9;27(5):516-29. doi: 10.1016/j.devcel.2013.11.001.

Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.

Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, Charron E, Weiss WA, Smirnov IV, Song JS, Olshen AB, Cha S, Zhao Y, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science. 2014 Jan 10;343(6167):189-93. doi: 10.1126/science.1239947. Epub 2013 Dec 12.

The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.

Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Ishikawa S, Aburatani H, Fukayama M, Niki T, Yasuda Y. The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway. Oncol Rep. 2014 Feb;31(2):619-24. doi: 10.3892/or.2013.2899. Epub 2013 Dec 5.

H3F3A K27M mutations in thalamic gliomas from young adult patients.

Aihara K, Mukasa A, Gotoh K, Saito K, Nagae G, Tsuji S, Tatsuno K, Yamamoto S, Takayanagi S, Narita Y, Shibui S, Aburatani H, Saito N. H3F3A K27M mutations in thalamic gliomas from young adult patients. Neuro Oncol. 2014 Jan;16(1):140-6. doi: 10.1093/neuonc/not144. Epub 2013 Nov 26.

Pathophysiological response to hypoxia – from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.

Lee YH, Iijima M, Kado Y, Mizohata E, Inoue T, Sugiyama A, Doi H, Shibasaki Y, Kodama T. Pathophysiological response to hypoxia – from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes. Biochem Biophys Res Commun. 2013 Nov 29;441(4):1011-7. doi: 10.1016/j.bbrc.2013.11.014. Epub 2013 Nov 12.

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes.

Haferlach T, Nagata Y, Grossmann V, Okuno Y, Bacher U, Nagae G, Schnittger S, Sanada M, Kon A, Alpermann T, Yoshida K, Roller A, Nadarajah N, Shiraishi Y, Shiozawa Y, Chiba K, Tanaka H, Koeffler HP, Klein HU, Dugas M, Aburatani H, Kohlmann A, et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia. 2014 Feb;28(2):241-7. doi: 10.1038/leu.2013.336. Epub 2013 Nov 13.

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.

Muto T, Sashida G, Oshima M, Wendt GR, Mochizuki-Kashio M, Nagata Y, Sanada M, Miyagi S, Saraya A, Kamio A, Nagae G, Nakaseko C, Yokote K, Shimoda K, Koseki H, Suzuki Y, Sugano S, Aburatani H, Ogawa S, Iwama A. Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders. J Exp Med. 2013 Nov 18;210(12):2627-39. doi: 10.1084/jem.20131144. Epub 2013 Nov 11.

Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by Jumonji domain containing 1A (JMJD1A) homodimer.

Goda S, Isagawa T, Chikaoka Y, Kawamura T, Aburatani H. Control of histone H3 lysine 9 (H3K9) methylation state via cooperative two-step demethylation by Jumonji domain containing 1A (JMJD1A) homodimer. J Biol Chem. 2013 Dec 27;288(52):36948-56. doi: 10.1074/jbc.M113.492595. Epub 2013 Nov 8.

A baculoviral display system to assay viral entry.

Iida M, Yoshida T, Watari A, Yagi K, Hamakubo T, Kondoh M. A baculoviral display system to assay viral entry. Biol Pharm Bull. 2013;36(11):1867-9.

A major role for RCAN1 in atherosclerosis progression.

Mendez-Barbero N, Esteban V, Villahoz S, Escolano A, Urso K, Alfranca A, Rodriguez C, Sanchez SA, Osawa T, Andres V, Martinez-Gonzalez J, Minami T, Redondo JM, Campanero MR. A major role for RCAN1 in atherosclerosis progression. EMBO Mol Med. 2013 Dec;5(12):1901-17. doi: 10.1002/emmm.201302842. Epub 2013 Oct 15.

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.

Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T, Hamakubo T. Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. J Biol Chem. 2013 Nov 15;288(46):33292-302. doi: 10.1074/jbc.M113.500397. Epub 2013 Oct 7.

Identification of Wilms’ tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.

Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T, Hamakubo T. Identification of Wilms’ tumor 1-associating protein complex and its role in alternative splicing and the cell cycle. J Biol Chem. 2013 Nov 15;288(46):33292-302. doi: 10.1074/jbc.M113.500397. Epub 2013 Oct 7.

Functions and regulation of MUC13 mucin in colon cancer cells.

Gupta BK, Maher DM, Ebeling MC, Stephenson PD, Puumala SE, Koch MR, Aburatani H, Jaggi M, Chauhan SC. Functions and regulation of MUC13 mucin in colon cancer cells. J Gastroenterol. 2014 Oct;49(10):1378-91. doi: 10.1007/s00535-013-0885-z. Epub 2013 Oct 7.

G protein-dependent basal and evoked endothelial cell vWF secretion.

Rusu L, Andreeva A, Visintine DJ, Kim K, Vogel SM, Stojanovic-Terpo A, Chernaya O, Liu G, Bakhshi FR, Haberichter SL, Iwanari H, Kusano-Arai O, Suzuki N, Hamakubo T, Kozasa T, Cho J, Du X, Minshall RD. G protein-dependent basal and evoked endothelial cell vWF secretion. Blood. 2014 Jan 16;123(3):442-50. doi: 10.1182/blood-2013-03-489351. Epub 2013 Sep 30.

1 / 41234