Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.

Suzuki T, Tsuzuku J, Hayashi A, Shiomi Y, Iwanari H, Mochizuki Y, Hamakubo T, Kodama T, Nishitani H, Masai H, Yamamoto T. Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob. J Biol Chem. 2012 Nov 23;287(48):40256-65. doi: 10.1074/jbc.M112.353805. Epub 2012 Oct 12.

Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages.

Kumamoto S, Kushiyama A, Nakatsu Y, Sakoda H, Fujishiro M, Iwashita M, Ohno H, Zhang J, Guo Y, Aburatani H, Kamata H, Nishimura F, Asano T. Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages. Obes Res Clin Pract. 2012 Oct-Dec;6(4):e263-346. doi: 10.1016/j.orcp.2012.05.005.

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

Ohta Y, Nishiyama A, Wada Y, Ruan Y, Kodama T, Tsuboi T, Tokihiro T, Ihara S. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Aug;86(2 Pt 1):021918. Epub 2012 Aug 21.

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.

Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R. Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16.

A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network.

Tsuji S, Ihara S, Aburatani H. A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network. BMC Syst Biol. 2012 Sep 15;6:124. doi: 10.1186/1752-0509-6-124.

The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Nasu-Nishimura Y, Todo T, Ino Y, Saito N, Aburatani H, Funato K, Echizen K, Sugano H, Haruta R, Matsui M, Takahashi R, Manabe E, Oda T, Akiyama T. The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells. Oncogene. 2013 Aug 15;32(33):3840-5. doi: 10.1038/onc.2012.399. Epub 2012 Sep 10.

Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene.

Matsuda S, Kuwako K, Okano HJ, Tsutsumi S, Aburatani H, Saga Y, Matsuzaki Y, Akaike A, Sugimoto H, Okano H. Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. J Neurosci. 2012 Sep 5;32(36):12543-57.

Functional reconstitution of olfactory receptor complex on baculovirus.

Mitsui K, Sakihama T, Takahashi K, Masuda K, Fukuda R, Hamana H, Sato T, Hamakubo T. Functional reconstitution of olfactory receptor complex on baculovirus. Chem Senses. 2012 Nov;37(9):837-47. doi: 10.1093/chemse/bjs067. Epub 2012 Sep 5.

Increased expression and aberrant localization of mucin 13 in metastatic colon cancer.

Gupta BK, Maher DM, Ebeling MC, Sundram V, Koch MD, Lynch DW, Bohlmeyer T, Watanabe A, Aburatani H, Puumala SE, Jaggi M, Chauhan SC. Increased expression and aberrant localization of mucin 13 in metastatic colon cancer. J Histochem Cytochem. 2012 Nov;60(11):822-31. doi: 10.1369/0022155412460678. Epub 2012 Aug 20.

Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium.

Yuda K, Takahashi H, Inoue T, Ueta T, Iriyama A, Kadonosono K, Tamaki Y, Aburatani H, Nagai R, Yanagi Y. Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium. Am J Pathol. 2012 Oct;181(4):1464-72. doi: 10.1016/j.ajpath.2012.06.028. Epub 2012 Jul 27.

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.

Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M, Motohashi H. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell. 2012 Jul 10;22(1):66-79. doi: 10.1016/j.ccr.2012.05.016.

COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells.

Pandya K, Kohro T, Mimura I, Kobayashi M, Wada Y, Kodama T, Smithies O. COUP-TFI and -TFII nuclear receptors are expressed in amacrine cells and play roles in regulating the differentiation of retinal progenitor cells. Gene Expr. 2012;15(4):183-98.

The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.

Matsuura Y, Hatakeyama K, Imamura T, Tsuruda T, Shibata Y, Kodama T, Kitamura K, Asada Y. The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Atheroscler Thromb. 2012;19(9):837-45. Epub 2012 Jul 11.

Epstein-Barr virus infection as an epigenetic driver of tumorigenesis.

Kaneda A, Matsusaka K, Aburatani H, Fukayama M. Epstein-Barr virus infection as an epigenetic driver of tumorigenesis. Cancer Res. 2012 Jul 15;72(14):3445-50. doi: 10.1158/0008-5472.CAN-11-3919. Epub 2012 Jul 3.

Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages.

Kudo S, Caaveiro JM, Miyafusa T, Goda S, Ishii K, Matsuura T, Sudou Y, Kodama T, Hamakubo T, Tsumoto K. Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to upregulation of nitric oxide and interferon-gamma production by tumor-associated macrophages. Mol Biosyst. 2012 Aug;8(8):2050-3. doi: 10.1039/c2mb25161b. Epub 2012 Jun 7.

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin.

Kudo S, Caaveiro JM, Miyafusa T, Goda S, Ishii K, Matsuura T, Sudou Y, Kodama T, Hamakubo T, Tsumoto K. Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin. Mol Biosyst. 2012 Aug;8(8):2050-3. doi: 10.1039/c2mb25161b. Epub 2012 Jun 7.