Annexin II represents metastatic potential in clear-cell renal cell carcinoma.

Ohno Y, Izumi M, Kawamura T, Nishimura T, Mukai K, Tachibana M. Annexin II represents metastatic potential in clear-cell renal cell carcinoma. Br J Cancer. 2009 Jul 21;101(2):287-94. Epub 2009 Jun 9.PMID: 19513064

Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204).

Tachibana K, Takeuchi K, Inada H, Yamasaki D, Ishimoto K, Tanaka T, Hamakubo T, Sakai J, Kodama T, Doi T. Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204). Biochem Biophys Res Commun. 2009 Nov 20;389(3):501-5. doi: 10.1016/j.bbrc.2009.09.018. Epub 2009 Sep 11.

Regulation of the human SLC25A20 expression by peroxisome proliferator-activated receptor alpha in human hepatoblastoma cells.

Tachibana K, Takeuchi K, Inada H, Yamasaki D, Ishimoto K, Tanaka T, Hamakubo T, Sakai J, Kodama T, Doi T. Regulation of the human SLC25A20 expression by peroxisome proliferator-activated receptor alpha in human hepatoblastoma cells. Biochem Biophys Res Commun. 2009 Nov 20;389(3):501-5. doi: 10.1016/j.bbrc.2009.09.018. Epub 2009 Sep 11.

Expression of Dlk/Pref-1 defines a subpopulation in the oval cell compartment of rat liver.

Saito Y, Hamakubo T, Yoshida Y, Ogawa Y, Hara Y, Fujimura H, Imai Y, Iwanari H, Mochizuki Y, Shichiri M, Nishio K, Kinumi T, Noguchi N, Kodama T, Niki E. Expression of Dlk/Pref-1 defines a subpopulation in the oval cell compartment of rat liver. Neurosci Lett. 2009 Nov 6;465(1):1-5. doi: 10.1016/j.neulet.2009.08.074. Epub 2009 Sep 3.

Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients.

Saito Y, Hamakubo T, Yoshida Y, Ogawa Y, Hara Y, Fujimura H, Imai Y, Iwanari H, Mochizuki Y, Shichiri M, Nishio K, Kinumi T, Noguchi N, Kodama T, Niki E. Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients. Neurosci Lett. 2009 Nov 6;465(1):1-5. doi: 10.1016/j.neulet.2009.08.074. Epub 2009 Sep 3.

A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chem Biol. 2009 Aug 28;16(8):882-92. doi: 10.1016/j.chembiol.2009.07.007.

Bilirubin from heme oxygenase-1 attenuates vascular endothelial activation and dysfunction.

Komohara Y, Takemura K, Lei XF, Sakashita N, Harada M, Suzuki H, Kodama T, Takeya M. Bilirubin from heme oxygenase-1 attenuates vascular endothelial activation and dysfunction. Cancer Sci. 2009 Nov;100(11):2160-6. doi: 10.1111/j.1349-7006.2009.01296.x. Epub 2009 Jul 23.

Promoter-wide analysis of Smad4 binding sites in human epithelial cells.

Koinuma D, Tsutsumi S, Kamimura N, Imamura T, Aburatani H, Miyazono K. Promoter-wide analysis of Smad4 binding sites in human epithelial cells. Cancer Sci. 2009 Nov;100(11):2133-42. doi: 10.1111/j.1349-7006.2009.01299.x. Epub 2009 Jul 23.

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.

Hayashi I, Takatori S, Urano Y, Iwanari H, Isoo N, Osawa S, Fukuda MA, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T. Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease. J Biol Chem. 2009 Oct 9;284(41):27838-47. doi: 10.1074/jbc.M109.055061. Epub 2009 Aug 14.

Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.

Hayashi I, Takatori S, Urano Y, Iwanari H, Isoo N, Osawa S, Fukuda MA, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T. Single chain variable fragment against nicastrin inhibits the gamma-secretase activity. J Biol Chem. 2009 Oct 9;284(41):27838-47. doi: 10.1074/jbc.M109.055061. Epub 2009 Aug 14.

Inhibition of plasma lipid peroxidation by anti-atherogenic antioxidant BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran.

Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T. Inhibition of plasma lipid peroxidation by anti-atherogenic antioxidant BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran. J Biol Chem. 2009 Oct 16;284(42):29109-24. doi: 10.1074/jbc.M109.041145. Epub 2009 Aug 12.

A novel tumor-targeted therapy using a claudin-4-targeting molecule.

Saeki R, Kondoh M, Kakutani H, Tsunoda S, Mochizuki Y, Hamakubo T, Tsutsumi Y, Horiguchi Y, Yagi K. A novel tumor-targeted therapy using a claudin-4-targeting molecule. Mol Pharmacol. 2009 Oct;76(4):918-26. doi: 10.1124/mol.109.058412. Epub 2009 Jul 28.

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice.

Inagaki T, Tachibana M, Magoori K, Kudo H, Tanaka T, Okamura M, Naito M, Kodama T, Shinkai Y, Sakai J. Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells. 2009 Aug;14(8):991-1001. doi: 10.1111/j.1365-2443.2009.01326.x. Epub 2009 Jul 15.

Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system.

Inagaki T, Tachibana M, Magoori K, Kudo H, Tanaka T, Okamura M, Naito M, Kodama T, Shinkai Y, Sakai J. Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system. Genes Cells. 2009 Aug;14(8):991-1001. doi: 10.1111/j.1365-2443.2009.01326.x. Epub 2009 Jul 15.

The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.

Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice. J Clin Invest. 2009 Aug;119(8):2257-70. doi: 10.1172/JCI35738. Epub 2009 Jul 13.

Lipid raft microdomains mediate class A scavenger receptor-dependent infection of Brucella abortus.

Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T. Lipid raft microdomains mediate class A scavenger receptor-dependent infection of Brucella abortus. J Clin Invest. 2009 Aug;119(8):2257-70. doi: 10.1172/JCI35738. Epub 2009 Jul 13.